Outcome following high-dose methotrexate in pregnancies misdiagnosed as ectopic.

Concurrent ultrasound-guided potassium chloride and systemic methotrexate injection in ectopic pregnancies with high B-HCG titers and fetal cardiac activity: Non surgical management of two cases

Methotrexate (MTX) is an accepted regimen for conservative treatment of unruptured ectopic pregnancy. However ,gestational sac greater than 3.5 cm, existence of cardiac activity and high titers of serum beta human chorionic gonadotrophin ( B-HCG) levels are relative contraindications of Mtx treatment. A 29-year-old, gravida 3, parity 1 and a 34-year-old nulliparous women presented with a compla...

عوامل پیش‌بینی کننده شکست درمان در رژیم تک دوز متوتروکسات در بیماران با حاملگی خارج رحمی

Background: The use of Methotrexate (MTX) is a good and common practice for the treatment of women who were diagnosed early with ectopic pregnancy (EP). The aim of this study is to determine the predictors of treatment failure with a single dose of MTX injection. Methods: In this quasi-experimental research, we studied 70 women with ectopic preg-nancies who were treated with MTX, according to ...

Fertility Outcome after Treatment of Unruptured Ectopic Pregnancy with Two Different Methotrexate Protocols

Methotrexate treatment of ectopic pregnancy: experience at nizwa hospital with literature review.

OBJECTIVES Ectopic pregnancy occurs when the embryo fails to implant within the uterine cavity. Methotrexate, a folic acid antagonist has been widely used to treat ectopic pregnancy. The aim of this study is to determine the efficacy of methotrexate treatment for ectopic pregnancies in our settings which will in-turn help us reduce maternal mortality and morbidity. METHODS This was a retrospe...

Success and spontaneous pregnancy rates following systemic methotrexate versus laparoscopic surgery for tubal pregnancies: a randomized trial.

OBJECTIVE To determine which treatment should be offered to women with a non-ruptured tubal pregnancy: a single dose of methotrexate (MTX) or laparoscopic surgery. DESIGN Prospective, randomized, open multicenter study. SETTING Seven Danish departments of obstetrics and gynecology. SAMPLE A total of 106 women diagnosed with ectopic pregnancy (EP). METHODS Between March 1997 and Septembe...